Hauv tsab xov xwm dhau los, peb tau tham txog PLLA;
Lub sijhawm no, peb yuav tham txog lwm cov khoom siv rov ua dua tshiab -PCL.
PCL yog cov khoom siv hluavtaws aliphatic polyester biopolymer nrog biocompatibility zoo heev, biodegradability, thiab absorbability.
Hauv cov tshuaj kho kom zoo nkauj, PCL feem ntau yog siv rau hauv daim ntawv sib xyaw ntawm 'PCL microspheres + carboxymethyl cellulose sodium (CMC) gel,' ua ib qho qauv ntawm "scaffold + tam sim ntawd muab tub lim." Qhov no muab kev txhawb nqa rau collagen regeneration thaum tseem muab cov teebmeem tam sim ntawd.
Tom qab txhaj tshuaj, PCL microspheres ua rau mob me me, ua kom tawv nqaij kho hlwb. Vim tias PCL decomposes qeeb qeeb hauv daim tawv nqaij, nws tuaj yeem tsim cov collagen ntau lawm rau lub sijhawm ntev, qhov kev xav tau ua rau muaj kev cuam tshuam ntev dua -.
Ntau cov khoom lag luam hauv khw muaj PCL ua cov khoom tseem ceeb. Nws regenerative mechanism suav nrog txhua yam kev txhawb nqa los ntawm microspheres, txhawb collagen regeneration.
Cov txheej txheem degradation: PCL yog cov khoom siv biodegradable uas thaum kawg hloov mus rau carbon dioxide thiab dej los ntawm ester bond hydrolysis, thiab tuaj yeem tshem tawm tag nrho ntawm lub cev. Nws feem ntau siv CMC cov cab kuj yog metabolized nyob rau hauv kwv yees li 6-8 lub lis piam.
Cov khoom no haum rau leej twg?
Lawv tsim nyog rau cov tib neeg uas xav pom cov txiaj ntsig tam sim ntawd thiab tseem xav tau ntev - lub sij hawm collagen regeneration.
Lawv feem ntau siv los txhim kho nasolabial quav, lub puab tsaig, thiab sab plhu.